SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b402f57a5f12a45de861afb4b15638b751df62ca0b9be84830ff76d677c2db78' 
  AND token = 'uRG/buqMfN5LCucCB9ka4okcp5v6JcpEQuUrYcnhFCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}