SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b1ae9a7ac49deec7294500d04f97a5d92b5e1b59a341302a66aa0a601fe170' 
  AND token = 'V/OgB/5vu04SbrJ6YQYKlJTmxUM4qidANBBEoVrSk0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}