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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63ccaa60d284b40e9721f57d20510d7894c6387c3d0ad4aaaf348777c12b6280' 
  AND token = 'pzAWfS+2bryL5nbAoKtuTi1982xxWObqEEe5g48qOno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}