SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4914d3874693f39d6910e40c4887c178b1c5fb0f8f4693c9414f22335e1018c0' 
  AND token = 'ftoxh0oabZQ8f8iHt9rBQ9zrx+vjGiQcO7XdPkBL/J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}