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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de95d4f6a532a27c4e90fdf545ec3765b5c22c157ee75d8a5d2dc206018bc935' 
  AND token = 'Tef+5NdpVfsMLu78Lq0gW5nPd6c6MvJ2FflSb0MN9iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}