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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80fd27d7b8d8fc8f6b64f9650406671e786936cbfd27dff7f03e70ba28ed5ae' 
  AND token = 'Z9jfn+xq82gpIc7m7wCbYbnkvAJ6GNndVrV9U0DZ3sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}