SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6d5f1940067365b7c0be74ff6ef46efd6f5ed9f1748e0799250ad6363e3522' 
  AND token = 'xJbQCPv3NhSU7rvpUSm4JdbShLcwiehF95NmbbP0GX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}