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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377105581da498997171abf44bc3613ddd9fa2a5b23a25b08523cb189bba5fe7' 
  AND token = 'wgONUQFOtpQdyuNsThyTXGJ28b1qrQyDz8OxKgtiqL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}