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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294af942ac68647be8fdb3bae6b184ecec41a0e8187afa7d96b396706c30eba7' 
  AND token = '6KIo5TqYrrlbR07PG1TA5/j9WfzyU+6R6loqH3fFNIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}