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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6308753b9fd12e81e6c9a6127c77f5118fc03b8f3d5baf03213e15175d1c3249' 
  AND token = 'AhDDn5kBHwxD93yvReZZAitL/GrybRivk82EGvA2a0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}