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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718363c3ac97a96494243f3a1a4217db3651a75619e06323c57499ff1e6eace4' 
  AND token = 'iwKgLNEdUqRWMx59ovAmsquVTYd37S4mutq0uq+b4gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}