SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885b975872ee090f8f976d3db2be32b2314c1754b3b670ada4aa35a17134ae3e' 
  AND token = 'ZHSHwwvckpz0q27RiZ4/JMQAp1fgH7BUJMpgMc20O/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}