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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6047daa9d6f5690eebc70ef13d7bae1a72aec8e8f2773c8766423246b3a2a363' 
  AND token = 'HmVh3GJKuEIzXYO+vFpaBpsV071WyY04PfMVD33gmAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}