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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd019ba2462dfd5a6099a72c250953be82c5ca9b3c7489555a1af6621a9a0a069' 
  AND token = 'kpnZFdbM1i/P1v7YsQ/6NskZFrg/TsgTpbMSN8P+nPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}