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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '945483d527ba183a346b98dbaca67953b2920050c0040d439c62b1b8cad342eb' 
  AND token = 'XpI7uMph+Jn41xOtkute8JqKCiO1w8BsPhAQPDtlVQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}