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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e49ef9ea77e555e0a0015e99fccd5c0ffa77359f03f6ea5d1e57f1e924e0dd8' 
  AND token = 'V4NpseMUoYU7iBJWRa4t9wXcy47LWK7JzYpXwpbzofQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}