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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6b8623f7375a4f3c6c9d127681305483225022f8571540606736c2da421d19' 
  AND token = 'mAgPQB1H5VZzuD0kBXXxOZbHzg1arPxCMBmmnF34i2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}