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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a36fa7e023e4f1f0773843fa9fddcc0e4d6366a526fc7952b71c3e023d6b6f42' 
  AND token = '2uLuQP/W7bPg2i0UkMN15OCbBdDd6YDlAOLnWDWxMS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}