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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29649aa4d72894e0d7b94c858c1303d6e98f185cd1bf5d110790d70804eb573b' 
  AND token = 'v/6rXAK0DC5R1hQ70r1I5cpBp1RnlVgHoqp05VXtC2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}