SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b6c345c22768f2e967e689d75434e9630ca5c434a75d6965ba53fbd0aea118' 
  AND token = 'UXG+26XE5bm/covct7vt/VoC891GP/KcpK0pZFrd990=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}