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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24fb479b3223b31cd3b0ba0c8c64a1d8e227b2acdf5521b4ffe92696edeb222c' 
  AND token = 'B/QCEAxpL8STVs2KbSBFP0xVUAwNvqrRB1r5tqQiwuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}