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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d35a0cfeedb70a4d3dac6318e08753549db4d3a17890e15e7d60b38461fb78c' 
  AND token = 'O5kkrpV3ww+/lVJWDtQDebsm3P9sQOkKZy+CWO1KILg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}