SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c964f6817d027a7b528c2fe84e4249a6ea6c4d727e311b8ab805cfb0a4aa169' 
  AND token = 'rdh2y32wnPRYtJVGVdddtAHuaL9Z2bB6NCAmW6Kr05Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}