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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e99da9ca4c032e84f5280b24895cff43d238cd9804f1fee19e66b0c9dcabe00' 
  AND token = 'xVeItMYv78y1PDHZiKDSWV/dG5+LLdeI79lXUDkLnIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}