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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f57bdbe4abe032a6c1cd271f23fcda2f74dc27b19e7f0dee6bad493d5538f5' 
  AND token = 'DtHOSXcrbTaU0+lT4w5MMoXFkUHWHfbq1ZnP3GlIAIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}