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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd69e7ea79241753ad0108e1a46b987c89063e55722d96f24e9da33aa2772f5c4' 
  AND token = '/xrMrk9YR4jCxUQyn9/CXFCMBA2hRpfN6+1iWyXj+F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}