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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '912ce2e7d35ae387c7fcad10c289e1d848efe4a46ecdfb5dc740d825e3b99f46' 
  AND token = 'Wg1nSjqzsTuMgu7jedd1WTkdsK8BTkzuuG0Pygt7JdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}