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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3e4d851e7648161e6e5f29ffc06d419846b90d7d3dde05e0e9860e6642b361' 
  AND token = 'Ae/5DSLb6RMUxAYmMJ62gI6E7yZO0hMfjwxroCU1w54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}