SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b887a79dcadab0a4aaa606316f56d3a691d776a8dbfdbf4005ce3af4b645a380' 
  AND token = '1C0YgpOZq3WH+o9WsunUQC0PYJKc80yysB1epJlGP9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}