SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2140f1a5da197e83ee9d0d9868659f14d14028a7d11b05ed3d841e3e3d14336e' 
  AND token = 'VyAuXhThKOjZ/JLW78Xw6HB7iqwdn+op0TsBjFDo48s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}