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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c62f7a0f91e0e221f2f9c970393cb2cf0eb00a2549e19ba473e4cf1bbda1a316' 
  AND token = 'giIHtaDxc9KayP/iCGFhTeClZkZMFD0Msn+3/rF+HbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}