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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4c59eef12c89c6d9227f78cf016c9c1ce7fb564c8d48d9c205cefa7a319650' 
  AND token = 'wWOo8tsrUMRrrKZMmbfBbiGe+0JqC+u+/LtOioxk2X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}