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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c111b5a5ef540d93c63db45c6f65803742c9892fbc87df1d09eacbca1aeade0' 
  AND token = 'gYk4E4Xt6jq/xTp74WptnTabR3EOfw4HH76qakVcu4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}