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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '358ec6233027d82ad7354f41a9134c45a6b01cdc3e7a41c87263eb2e7d5e46dc' 
  AND token = 'gFp/tsWatj1E1XR/fKf/GQs+OTNrbMTZICotjBV4W3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}