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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0606257573a33cd69380354fa18afceeb427f0ff9d11c86a35616db851a391f2' 
  AND token = 'no6mQyHzyBXhcHqzx17CfPcPTJgyaoQPq+4qqJEwXog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}