SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc60a8f7a1943650c1575b91e2c27b5781cb512e12f94070b404bfe03ae44aad' 
  AND token = 'RF4ER9YHdcWsOjhAHCP3o062KPEntTioRmRFkgB1lDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}