SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0673e7a7252d69ac90e93e8f7d78333922fcc500ba37e72b1a606ed5c227e766' 
  AND token = 'NY8qYf8GfXBjP9visTcuTVm1RxkaLDF5Ci5B6Z8UPbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}