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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02d575fe0602ee79a11efbd44a1378a4e42677f0e0223287603e104e07fd2fa5' 
  AND token = 'jKmGAc5PQI3uCv/19OYyT5WOY8xjNjsXK8v5nu7DXkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}