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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8c152e172164c10704402d0f2769254902729595a13bd2f15a1b1075e5baa8' 
  AND token = 'RBK1hjMUlH51YCbnu0kLUcuRFnNB9Sp+Zn0Bjjvn5RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}