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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54777fd76c1c2febc4406b55237a581534827d74be3fd55ef64c1f24d4893d4' 
  AND token = 'u4Dfvm6dt6UD+23jvaWTUvZ0Dj+AhOPSs9izdIq838Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}