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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7940da282d4c8539485b9d4c1203081a4ee55c72b982a9d46d3e1c6de21cf46' 
  AND token = 'UatNv//MgCpW/vSv4zvoMN+0YS5l5X7ThJ+GnWF7Fmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}