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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220c1c4ca7fb94a58377ecd5e466f65303c18d293ead763f06bd6c9566349020' 
  AND token = '5rPu7/Bd6FeqZFPOkCuyVsUmMjPfIFdD4kypG+PABPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}