SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df47ce5b8be6fabcc8953d43bc606a1f2163d79c80e1e47c29084d9ab662a8e4' 
  AND token = 'Ran2Oatg8IlykuzbKMYH7YRlAfgeX2xEKzkFEqQULEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}