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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c22116ce21b3731c6471f61385d37a101c21ccff4c498052c2f1c431923862' 
  AND token = 'N+vkWgifkH/ZSJIBspWJyagLRqcNkm1FnoD7j9CNyNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}