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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fc7b5a9fdd8b361fe0a58189088c44b5b8c5fd1ed2e1f55cf0ea85c1aad44a' 
  AND token = 't8e2klMCqUijusxJ1NaqP7TFiBM27jq1owahgSeAFFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}