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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd997c935f22989f6684b31acaac92f9586aef8453ea4e23095590bd051c37e' 
  AND token = '/IjnrlKxyF7ogM4pbiCO7piivLR4GLVG+UMNTSD1bMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}