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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41fd2132a7b4a6e2e0afc6dcf41445a6d2cb10e05748cfa16e30aafc5e56439' 
  AND token = '2R5oTOYNdYthUQNZoEdY1zmoj3+GtdYg/SYN6diKM9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}