SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f70949c3d05dcb66477981e6f7c4aca26e1473b6badfce4b6454541cb33834' 
  AND token = 'EmTyhwpeHyMm8KcAoe3MfiwGz3u/marpeaNqsKJvmBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}