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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76a650136067ef7c1785e5f00cafa8eb1fe60f3b13fcf26f2a5142d7a646b4d1' 
  AND token = 'b9t0PeEadZWGN9a6B209oA/NH4VV5tFVGWRKoQ/TCQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}