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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc2ddbd1fedcda593a655643a4723c98cdda9cda11e00c5a6f1c48c0438437c6' 
  AND token = 'kdMshxrfcn47AHYJFRYbpZvTEYyqJ/YvYXnxbvgr6+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}